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PlayStation 2 "E" Games
- Eagle Eye Golf
- Ecco The Dolphin: Defender of the Future
- Echo Night: Beyond
- Ed, Edd n Eddy: The Mis-Edventures
- Egg Mania: Eggstreme Madness
- eJay Clubworld
- El Tigre: The Adventures of Manny Rivera
- Enclave II
- Endgame
- Enter the Matrix
- Enthusia Professional Racing
- Ephemeral Fantasia
- Eragon
- Escape From Monkey Island
- ESPN College Hoops
- ESPN College Hoops 2K5
- ESPN International Track & Field
- ESPN International Winter Sports 2002
- ESPN Major League Baseball 2004
- ESPN MLS Extra Time
- ESPN National Hockey Night
- ESPN National Hockey Night 2002
- ESPN NBA 2 Night 2002
- ESPN NBA 2K5
- ESPN NBA 2Night
- ESPN NBA Basketball
- ESPN NFL 2K5
- ESPN NFL Football
- ESPN NFL Prime Time 2002
- ESPN NHL 2K5
- ESPN NHL Hockey
- ESPN Winter X Games: Snowboarding
- ESPN Winter X-Games Snowboarding 2002
- ESPN X Games: Skateboarding
- ET: Return to the Green Planet
- Eternal Ring
- Eureka Seven - Vol 1: The New Wave
- Eureka Seven Vol. 2: The New Vision
- Eve of Extinction
- Everblue 2
- Evergrace
- Everquest Online Adventures: Frontiers
- Evil Dead: A Fistful of Boomstick
- Evil Dead: Regeneration
- Evil Twin
- Evolution Skateboarding
- Evolution Snowboarding
- Extermination
- Extreme Pool
- Eye Toy
- Eye Toy: Chat
- Eye Toy: Operation Spy
- EyeToy: Groove